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Atrophy in the cerebral hemispheres,cerebellum,and brain stem was significantly greater in patients with FA than in control subjects,and the degree of atrophy correlated with the clinical severity.Local cerebral metabolic rate for glucose declined significantly from the initially elevated levels in the thalamus,cerebellum,and brain stem in correlation with increasing clinical severity.The structure and function of wide- spread brain regions including the cerebral hemispheres are abnormal in FA,and these abnormalities correlate with the clinical severity. |
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CAT scan
CAT scan,abnormal
CAT scan,emission
CAT scan,emission,abnormal
cerebral glucose metabolism
Friedreich's ataxia
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